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Diagnostic problems in thromboembolism

O R Odegård

    Folia Haematologica (Leipzig, Germany : 1928)
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Blood tests cannot detect current venous thrombosis or a prethrombotic state. Direct thrombus visualization, like phlebography, is essential for diagnosis, though tests aid in identifying coagulation disorders.

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    Thrombosis research·1977

    Area of Science:

    • Medical Diagnostics
    • Hematology
    • Vascular Medicine

    Background:

    • Venous thrombosis presents diagnostic challenges.
    • The role of laboratory blood tests in diagnosing venous thrombosis is debated.
    • Identifying a prethrombotic state remains difficult.

    Purpose of the Study:

    • To evaluate the diagnostic utility of blood tests for venous thrombosis.
    • To emphasize the necessity of direct thrombus visualization.
    • To clarify the role of coagulation profiles in thrombosis management.

    Main Methods:

    • Review of pathogenetic aspects and diagnostic problems in venous thrombosis.
    • Emphasis on the value and limitations of blood tests.
    • Discussion of direct thrombus demonstration methods, particularly phlebography.

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    Main Results:

    • Blood tests are insufficient for detecting ongoing thrombosis.
    • Blood tests cannot identify a prethrombotic state.
    • Phlebography is highlighted as the preferred method for direct thrombus demonstration.

    Conclusions:

    • Direct demonstration of the thrombus is crucial for diagnosing venous thrombosis.
    • Blood tests are valuable for assessing the 'coagulation profile'.
    • Coagulation tests can help identify specific deficiencies like antithrombin III deficiency or subnormal fibrinolytic activity.