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Pharmacy, pharmaceutics and modern drug delivery
American Journal of Hospital Pharmacy
|August 1, 1976
Summary
This review covers advancements in controlled drug delivery systems and the prodrug approach. Pharmacists should understand these drug delivery mechanisms to uphold their expertise.
Area of Science:
- Pharmaceutical Sciences
- Drug Delivery Systems
Background:
- Review of recent advancements in pharmaceutical drug delivery.
- Exploration of controlled release technologies and prodrug strategies.
Purpose of the Study:
- To provide an overview of innovative drug delivery methods.
- To highlight the importance of understanding prodrugs and controlled release.
Main Methods:
- Literature review of controlled delivery systems.
- Discussion of prodrug examples like epinephrine esterification and 2-PAM dihydro form.
Main Results:
- Detailed discussion of controlled-release oral products, silastic devices, and membrane-medicated systems.
- Illustrative examples of the prodrug approach using specific chemical modifications.
Conclusions:
- Pharmacists must study drug release patterns and prodrug pharmaceutics.
- Emphasizes the pharmacist's role in managing advanced drug delivery technologies.