Time and dose for optimum radioactive phosphorus uptake measurement in rabbit uveal melanoma

Radioactive phosphorus uptake (32P) testing was performed on implanted uveal melanomas in the rabbit to determine how the percentage uptake value was affected by the dose of 32P and by the interval of time between 32P administration and 32P counting. There was no difference in percentage uptake comparing doses of 50, 100, and 200 muCi/kg, but these were relatively high doses. There was no difference in the mean percentage uptake value at two, five, or nine days after 32P administration. The range of percentage uptake values widened with successive days.