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Intracellular calcium and Na+-Ca2+ exchange current in isolated toad pacemaker cells

Y K Ju1, D G Allen

  • 1Department of Physiology and Institute of Biomedical Research, University of Sydney (F13), NSW 2006, Australia.

The Journal of Physiology
|June 6, 1998
PubMed
Summary

This study reveals that intracellular calcium concentration ([Ca2+]i) is crucial for the spontaneous firing rate of pacemaker cells in cane toads. Manipulating calcium levels directly impacts heart rate, highlighting the role of calcium handling in cardiac rhythm.

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