Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Activation of coagulation in decompression illness

A Boussuges1, E Succo, I Juhan-Vague

  • 1Service de Réanimation Médicale et d'Hyperbarie, Hopital Salvator, Marseille, France.

Aviation, Space, and Environmental Medicine
|March 10, 1998
PubMed
Summary

Decompression illness (DCI) did not show significant coagulation activation in divers, even with neurological symptoms. Further research is needed to understand the role of hemostasis in DCI physiopathology.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Surgical emphysema reduction: A viable alternative in the era of endobronchial valves].

Revue des maladies respiratoires·2025
Same author

Adaptative mechanism of the equilibrative nucleoside transporter 1 (ENT-1) and blood adenosine levels in elite freedivers.

European journal of applied physiology·2020
Same author

Observational study of potential risk factors of immersion pulmonary edema in healthy divers: exercise intensity is the main contributor.

Sports medicine - open·2017
Same author

Hyperoxia and hypergravity are independent risk factors of atelectasis in healthy sitting humans: a pulmonary ultrasound and SPECT/CT study.

Journal of applied physiology (Bethesda, Md. : 1985)·2016
Same author

Increased systemic blood pressure and arterial stiffness in young adults born prematurely.

Journal of developmental origins of health and disease·2014
Same author

Inter-limb changes in arterial function after intense cycling exercise.

International journal of sports medicine·2014

Area of Science:

  • Diving Medicine
  • Hematology
  • Physiopathology

Background:

  • Animal studies suggest circulating bubbles activate coagulation in decompression illness (DCI).
  • Hemostasis modifications are a suspected factor in DCI's underlying mechanisms.
  • Understanding coagulation's role in DCI is crucial for sports divers.

Purpose of the Study:

  • To investigate molecular hemostasis markers in divers suffering from DCI.
  • To compare coagulation parameters between DCI patients and healthy control divers.
  • To determine the correlation between coagulation activation and DCI severity or sequelae.

Main Methods:

  • Studied 25 divers with DCI and 15 control divers.
  • Measured platelet count, fibrinogen, antithrombin III, Thrombin Antithrombin III complexes, and D-Dimers.

Related Experiment Videos

  • Analyzed coagulation markers in relation to neurological, osteoarticular, and vestibular symptoms.

    • Main Results:

    • No significant differences in most coagulation parameters were found between DCI patients and controls.
    • Three divers with neurological DCI showed elevated D-Dimers (>500 ng/mL), indicating coagulation activation.
    • Coagulation activation was not correlated with the risk of sequelae or accident severity in osteoarticular or vestibular cases.

    Conclusions:

    • Coagulation activation does not appear to be a primary factor in the severity of decompression illness in sports divers.
    • Elevated D-Dimers in some neurological DCI cases warrant further investigation.
    • More research is required to clarify the role of hemostasis in DCI.