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Analysis of DNA adducts by capillary methods coupled to mass spectrometry: a perspective
1Department of Chemistry, Northeastern University, Boston, MA 02115, USA.
Journal of Chromatography. A
|March 10, 1998
Abstract:
The analysis of DNA adducts, important molecular biomarkers indicative of potential cellular damage by covalent attachment to DNA, is discussed. The paper focusses on a discussion of the current status in the analysis of DNA adducts via the use of capillary high-performance liquid chromatographic and capillary electrophoretic methods coupled to tandem mass spectrometry.