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[The prevalence of the main risk factors in hypertension patients]
Insights
This study identified key risk factors for hypertensive disease (HD) in 669 patients. Multiple risk factors interact, worsening the condition through a "mutual aggravation" phenomenon.
Area of Science:
- Cardiology
- Hypertension Research
Context:
- Investigated risk factors in 669 patients with Stage I and II hypertensive disease (HD) based on WHO classification.
- Developed a specific risk-factor module for hypertensive disease.
- Identified prevalent risk factors including meteorolability, hereditary predisposition, hyperlipidemia, and hypercoagulation.
Purpose:
- To determine the incidence and impact of various risk factors on hypertensive disease.
- To explore the pathogenetic relationship between risk factors and the clinical presentation of HD.
- To elucidate the "mutual aggravation" phenomenon among co-existing risk factors in HD patients.
Summary:
- Meteorolability (72.5%), hereditary predisposition (62.3%), and hyperlipidemia (53.8%) were the most common risk factors identified in the study population.
- A significant pathogenetic link was established between the number and aggressiveness of risk factors and the clinical pattern of hypertensive disease.
- The study revealed a "mutual aggravation" phenomenon where multiple risk factors negatively influence each other, exacerbating HD development.
Impact:
- Provides a comprehensive understanding of risk factor interplay in hypertensive disease.
- Highlights the importance of addressing multiple risk factors concurrently for effective hypertension management.
- Informs clinical practice and public health strategies aimed at preventing and managing hypertensive disease.
Abstract:
Incidence was studied of risk factors (RF) in 669 patients with stage I and II hypertensive disease (as per WHO classification). There has been developed a risk-factor HD module. The prevailing RFs among HD patients include meteorolability, hereditary predisposition, hyperlipidemia, blood hypercoagulation, surplus body mass, hypodynamia, mental/nervous overstrain, consumption of salt going up, smoking, hyperglycemia, alcoholic liquor abuse, with n = 485 (72.5%), 417 (62.3%), 360 (53.8%), 335 (50.1%), 324 (48.4%0), 218 (32.6%), 166 (24.8%), 144 (21.5%), 84 (12.6%), 39 (5.8%), 8 (1.2%) respectively. A pathogenetic relation was found between RFs and HD clinical pattern determined by the RFs number and aggressiveness. The "mutual aggravation" phenomenon has been disclosed, its main point being to the effect that if a HD patient has several RFs, these would create certain conditions for development of each of them through affecting each other in a negative way.