[A clinico-biochemical basis for the use of enterosorption in severe craniocerebral trauma]

Particular features were studied of the time course of changes in biochemical parameters characterizing endogenous intoxication in severe craniocerebral injury in patients greater than 45 years old. In group 1 patients displaying high values for endotoxicosis, there has been noted lowering of the above values after enterosorption over the immediate twenty-four hours following the injury, accompanied by regression of neurological symptomatology. In group 2 those who had sustained the injury and had normal or moderately elevated values for endotoxicosis on the first day, the latter were found to be on the increase in the time course of acute period of the injury. This necessitated including enterosorption into the therapeutic complex to be inaugurated in all those patients having sustained severe craniocerebral injury, within the above age bracket.