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Remission of cancer chemotherapy-induced emesis during antidepressant therapy with nefazodone
H R Khouzam1, A J Monteiro, M E Gerken
1VA Medical Center, Manchester, New Hampshire 03104-4098, USA.
Psychosomatic Medicine
|March 10, 1998
Abstract
Objective:
To emphasize the importance of treating a major depressive episode in an elderly patient with small cell lung cancer (SCLC).
Method:
A case report is described to illustrate the importance of treating depression in an elderly patient with SCLC undergoing chemotherapy.
Results:
During the course of antidepressant therapy with nefazodone, the patient also experienced a remission of cancer chemotherapy-induced emesis.
Conclusions:
This case report suggests that the remission of emesis could be related to the 5-hydroxytryptamine (5-HT) antagonistic property of nefazodone.