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Papillary eccrine adenoma with a pomegranate-like appearance
M Ambo1, M Kumakiri, H Kobayashi
1Department of Dermatology, Hokkaido University School of Medicine, Sapporo, Japan.
The Journal of Dermatology
|March 11, 1998
Summary
Papillary eccrine adenoma (PEA) is a rare skin tumor. This case report details its unique presentation and confirms its origin from eccrine sweat ducts through histopathological and immunohistochemical analysis.
Area of Science:
- Dermatopathology
- Oncology
Background:
- Papillary eccrine adenoma (PEA) is a rare benign cutaneous neoplasm.
- Few cases have been reported, highlighting the need for further documentation.
Observation:
- A 58-year-old Japanese man presented with a PEA.
- The tumor exhibited marked hyperkeratosis and pits, resembling a pomegranate.
- Histopathology revealed intradermal tubular structures with papillary projections and spiral ducts within hyperkeratosis.
Findings:
- The study confirmed the diagnosis of PEA based on histopathological and immunohistochemical findings.
- The observed keratinous structures corresponded to eccrine pores.
- The tumor's origin from eccrine sweat ducts was proposed.
Implications:
- This case contributes to the limited literature on PEA.
- Understanding the origin of PEA aids in accurate diagnosis and classification of cutaneous tumors.
- Further research may elucidate the specific pathways involved in PEA development.