[Diffuse B-cell lymphoma associated with hemophagocytic syndrome]

The patient was a 49-year-old woman who came to our hospital with a chief complaint of fever. She was admitted due to hepatosplenomegaly and pancytopenia. We diagnosed hemophagocytic syndrome based on histological examination of the bone marrow. She was treated with antibiotics and the CHOP regimen, resulting in solution of her condition. Two months later, lymphadenopathy and pancytopenia were recognized. Pathological examination of a lymph node revealed diffuse large B-cell lymphoma. B-cell lymphoma with hemophagocytosis was diagnosed. We present here a rare case of B-cell lymphoma associated with hemophagocytic syndrome.