Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[TNM classification--pediatric tumors]

Y Hayashi1, R Ohi, I Okabe

  • 1Dept. of Pediatric Surgery, Tohoku University School of Medicine.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|March 11, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcome of hepatoblastoma treated with the JPLT-1 (Japanese Study Group for Pediatric Liver Tumor) Protocol-1: A report from the Japanese Study Group for Pediatric Liver Tumor.

Journal of pediatric surgery·2002
Same author

Supercharged gastric tube pull-up procedure for total esophageal reconstruction.

Annals of plastic surgery·2001
Same author

Expression of the intermediate filament nestin in gastrointestinal stromal tumors and interstitial cells of Cajal.

The American journal of pathology·2001
Same author

The role of oval cells in rat hepatocyte transplantation.

Transplantation·2000
Same author

Inhibition by an angiogenesis inhibitor, TNP-470, of the growth of a human hepatoblastoma heterotransplanted into nude mice.

Journal of pediatric surgery·2000
Same author

The evaluation of meconium disease by distribution of cathepsin D in intestinal ganglion cells.

Pediatric surgery international·2000
Same journal

[A Case of Pulmonary Epithelioid Hemangioendothelioma Associated with Multiple Cancers].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[Long-Term Survival in Three Cases with Pulmonary Metastases from Colorectal Cancer Given Low-Dose S-1 Under a Regimen Combining a Carbohydrate-Restricted Ketogenic Diet, Metformin, Vitamin D, Eicosapentaenoic Acid, and Other Complementary Therapies].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[Preventive Effect of Saline Eye Wash for Eye Symptoms Due to High-Dose and Intermediate-Dose Cytarabine Therapy].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[Examination of Factors Affecting the Efficacy of Naldemedine Tosilate Tablets for Opioid-Induced Constipation].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[Recent Advances in the Treatment of HER2-Altered Solid Tumors].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same journal

[BRAF-Mutant Solid Tumor].

Gan to kagaku ryoho. Cancer & chemotherapy·2026
See all related articles

The postsurgical TNM staging systems, particularly the Japanese pTNM, effectively assess prognoses for pediatric cancers like neuroblastoma and Wilms tumor. Clinical TNM staging alone was insufficient for determining disease extent.

Area of Science:

  • Pediatric Oncology
  • Cancer Staging
  • Tumor Classification

Context:

  • Established TNM (Tumor, Node, Metastasis) staging systems for pediatric cancers (neuroblastoma, nephroblastoma, soft tissue sarcomas) were introduced in 1982.
  • Japanese TNM Committee developed novel postsurgical TNM (pTNM) systems for neuroblastoma and nephroblastoma, and clinical and postsurgical TNM for infant liver carcinoma.
  • These Japanese systems were informed by staging criteria from the Japanese Society of Pediatric Surgeons.

Purpose:

  • To evaluate the effectiveness of existing and newly proposed TNM staging systems for pediatric malignancies.
  • To assess the utility of clinical TNM (cTNM) versus postsurgical TNM (pTNM) in predicting outcomes.
  • To explore the potential of subdividing the M category in neuroblastoma for refined staging.

Summary:

Related Experiment Videos

  • The study analyzed neuroblastoma, Wilms tumor, and hepatoblastoma cases to assess TNM system effectiveness.
  • Postsurgical TNM (pTNM) systems, especially the Japanese pTNM (J-pTNM), demonstrated significant effectiveness in predicting patient prognoses.
  • Clinical TNM (cTNM) systems were found to be inadequate for fully assessing the extent of disease.

Impact:

  • The findings support the enhanced prognostic value of postsurgical TNM staging in pediatric oncology.
  • Highlights the superiority of J-pTNM for neuroblastoma, Wilms tumor, and hepatoblastoma prognostication.
  • Suggests a need for refinement in clinical staging methods for pediatric cancers.