Related Experiment Video
Updated: Aug 8, 2026
Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats
Published on: July 1, 2016
Electroretinographic evaluation of Papillons with and without hereditary retinal degeneration
1Department of Medicine and Surgery, Swedish University of Agricultural Sciences, Uppsala.
Objective:
To evaluate the function of the outer retina in Papillons with and without hereditary retinal degeneration.
Animals:
45 Papillons, median age 1.7 (range, 0.8 to 5.1) years.
Procedure:
Complete physical and ophthalmic examinations were done prior to performing electroretinography under general anesthesia. Full-field electroretinograms (ERG) were recorded, using a special-purpose computer system. Eleven specific ERG responses were recorded, graphed, and evaluated, using age-matched Papillons.
Results:
Severely decreased retinal function was detected in 8 Papillons. The youngest affected dog was 1.2 years old. In affected dogs, amplitudes of responses mainly originating from the rod system were severely decreased, compared with those originating from the cone system.
Conclusions:
Papillons represent another breed of dog affected by a hereditary photoreceptor degeneration that can be detected at an early age by using ERG. A reliable age for diagnosis using ERG is considered to be 1.5 years.
Clinical Relevance:
Through and precise ERG procedures and protocols are needed to reliably obtain an early diagnosis of progressive retinal atrophy.
More Related Videos
09:10Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium
Published on: July 14, 2020
08:38Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards
Published on: September 3, 2020