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Translocation (5;10)(q13;q26) in acute monoblastic leukemia
F Pernice1, C Musolino, G Mazza
1Cattedra e Divisione di Medicina Interna, Università degli Studi di Messina, Italy.
Cancer Genetics and Cytogenetics
|March 12, 1998
Abstract:
We report a case of acute monoblastic leukemia [French-American-British (FAB) M5a] observed in a 38-year-old man and associated at diagnosis with a t(5;10)(q13;q26) found in cells from a bone marrow culture. The patient survived only 2 months after diagnosis. t(5;10) as a solitary chromosome abnormality has not been previously reported in M5a, and, in the case that we describe, it appears to be correlated with a poor prognosis.