Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

On Miettinen's multivariate confounder score

D Strauss1

  • 1Department of Statistics, University of California, Riverside 92521, USA.

Journal of Clinical Epidemiology
|March 12, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Extreme storm events drive beach connectivity through headland bypassing.

The Science of the total environment·2025
Same author

Percutaneous cryoablation for desmoid fibromatosis: initial experience at a UK centre.

Clinical radiology·2022
Same author

Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Annals of oncology : official journal of the European Society for Medical Oncology·2021
Same author

Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up.

Annals of oncology : official journal of the European Society for Medical Oncology·2021
Same author

Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up<sup>☆</sup>.

Annals of oncology : official journal of the European Society for Medical Oncology·2021
Same author

Epithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts.

ESMO open·2021

Miettinen

Area of Science:

  • Epidemiology
  • Biostatistics
  • Medical Research Methodology

Background:

  • Regression models are used to assess treatment effects amidst confounding variables.
  • Stratification by discrete covariates is a common approach for analyzing treatment effects.
  • Miettinen's multivariate confounder score stratification method has been previously deemed flawed.

Purpose of the Study:

  • To re-evaluate the utility of multivariate confounder score stratification for comparing treatment and control groups.
  • To demonstrate the validity and practical benefits of this stratification approach.

Main Methods:

  • Utilizing a regression modeling framework to analyze treatment effects.
  • Applying stratification based on a multivariate confounder score.

Related Experiment Videos

  • Conducting graphical comparisons of treatment and control groups within strata.

    • Main Results:

    • Despite previous criticisms, multivariate confounder score stratification provides a sound basis for analysis.
    • This method facilitates a useful graphical comparison of treatment and control groups.
    • The approach remains relevant for understanding treatment effects in the presence of confounders.

    Conclusions:

    • The multivariate confounder score stratification method, contrary to prior beliefs, is a valid and useful technique.
    • This approach offers a sound graphical comparison for treatment effect assessment.
    • Revisiting and correctly applying this method can enhance epidemiological and biostatistical analyses.