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Atrial contribution to ventricular ejection in sequentially paced patients

J Kvasnicka1, M Tauchman, D Kovár

  • 1First Medical Department, Faculty Hospital, Faculty of Medicine, Charles University, Hradec Králové, Czech Republic.

Physiological Research
|January 1, 1996
PubMed
Summary
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This study introduces a new method to measure the atrial contribution to ventricular ejection in paced patients. This atrial contribution is dependent on the atrioventricular interval and is reproducible.

Area of Science:

  • Cardiology
  • Physiology

Background:

  • The atrial contribution to ventricular ejection is crucial for cardiac function.
  • Assessing this contribution in sequentially paced patients requires reliable quantitative methods.

Purpose of the Study:

  • To describe a novel method for the quantitative assessment of the atrial contribution to ventricular ejection.
  • To evaluate the atrioventricular interval dependency and reproducibility of this measurement.

Main Methods:

  • A new method was developed to measure the atrial contribution (AC).
  • AC was defined as the pulse pressure decrement (invasive arterial measurement) induced by temporarily switching off the atrial pacing impulse.
  • Measurements were performed in 17 sequentially paced patients.

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Main Results:

  • The atrial contribution (AC) was found to be dependent on the atrioventricular (AV) interval.
  • The method demonstrated good reproducibility (mean difference between measurements: 9.3%, S.D. 8.4%).
  • At a 170 ms AV interval, AC varied significantly: 29.3% in sick sinus syndrome, 27.0% in complete AV block, and 10.8% in complete AV block with heart dysfunction.

Conclusions:

  • A novel, reproducible method for quantifying the atrial contribution to ventricular ejection in sequentially paced patients has been established.
  • The atrial contribution is significantly influenced by the atrioventricular interval.
  • This method can differentiate cardiac function in patients with varying degrees of conduction abnormalities.