Related Experiment Videos
Distribution of the alpha7 nicotinic acetylcholine receptor subunit in the developing chick cerebellum
W M Kaneko1, L R Britto, J M Lindstrom
1Department of Neurosciences, University of California, San Diego, La Jolla 92093-0608, USA. wkaneko@ucsd.edu
Brain Research. Developmental Brain Research
|March 13, 1998
Abstract:
Previous studies of the nicotinic acetylcholine receptor (nAChR) subunits in adult mammalian and avian brains have demonstrated a spatially restricted distribution of these subunits; little, however, is known about the nAChR subunit developmental distribution. The present study demonstrated a transient pattern of distribution of the neuronal nAChR subunit, alpha7, in the developing chick cerebellum by using immunohistochemical techniques. This transient distribution may suggest a critical period for the development of the cholinergic system in the cerebellum.