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Prothipendylhydrochloride-induced priapism: case report
D Michielsen1, G Lamberts, V De Boe
1Department of Urology, Academic Hospital, AZ-VUB, Brussels, Belgium.
Acta Urologica Belgica
|March 14, 1998
Summary
Priapism, a prolonged erection, can occur after taking prothipendylhydrochloride. This is the first reported instance linking this phenothiazine medication to the condition.
Area of Science:
- Pharmacology
- Urology
- Clinical Medicine
Background:
- Phenothiazines are a class of drugs with various therapeutic uses.
- Priapism is a medical emergency characterized by persistent penile erection.
Observation:
- A patient developed priapism following oral administration of prothipendylhydrochloride.
- This adverse drug event was noted in the clinical setting.
Findings:
- This case represents the first documented instance of priapism associated with prothipendylhydrochloride.
- The phenothiazine derivative prothipendylhydrochloride is implicated as a potential cause of priapism.
Implications:
- Clinicians should be aware of priapism as a potential side effect of prothipendylhydrochloride.
- Further investigation into the mechanisms linking phenothiazines to priapism may be warranted.