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Comparative study of meniscus replacement using autogenous auricular cartilage versus Zenoderm
A M Hindy1, M A Shaker, R M Mounir
1Oral Surgery Department, Faculty of Oral and Dental Medicine, Cairo University.
Egyptian Dental Journal
|January 1, 1995
Summary
This study compared autogenous ear cartilage and Zenoderm grafts for temporomandibular joint meniscus replacement in dogs. Zenoderm showed better integration and functional adaptation compared to autogenous cartilage.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Medicine
- Veterinary Surgery
Background:
- Temporomandibular joint (TMJ) meniscus defects can impair joint function.
- Autogenous and allogeneic grafts are explored for meniscus reconstruction.
Purpose of the Study:
- To histologically compare autogenous ear cartilage and Zenoderm grafts for TMJ meniscus replacement in dogs over 3 months.
- To evaluate graft integration and functional adaptation.
Main Methods:
- Unilateral TMJ meniscus replacement in 12 mongrel dogs using either autogenous ear cartilage or Zenoderm.
- Histological evaluation at 3 months post-surgery.
Main Results:
- Autogenous cartilage was gradually replaced by fibrous tissue, with muscle attachment by 3 months.
- Zenoderm was replaced by vascular fibrous tissue, showing earlier muscle attachment (1 month) and good functional adaptation.
- No bone architecture changes were observed with either graft.
Conclusions:
- Zenoderm demonstrates superior integration and functional adaptation compared to autogenous ear cartilage for TMJ meniscus replacement in dogs.
- Further research may explore Zenoderm's potential in human TMJ reconstruction.
