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Adrenoleukodystrophy--unusual CT and MR findings in two siblings. Case reports
P C Sundgren1, G Blennow, E Englund
1Department of Diagnostic Radiology, University Hospital, Lund, Sweden.
Purpose:
To describe the unusual appearance of adrenoleukodystrophy (ALD) in MR imaging.
Material And Methods:
An analysis was made of MR findings, histopathology and clinical course in the cases of two brothers with ALD.
Results:
The older brother presented with frontal contrast-enhanced lesions, including a cyst. These were initially misinterpreted as a tumour at both radiology and pathology. The correct diagnosis was made after the discovery of very-long-chain fatty acids in the blood. The younger brother presented initially with involvement of various segments of the corticospinal tract.
Conclusion:
It is important that the radiologist be aware of the variants of ALD in MR imaging so as to avoid diagnostic mistakes.