Related Experiment Videos
[Effects of calcinogenic plants--qualitative and quantitative evaluation]
1Departmento de Farmacologia, Universidade Federal do Rio Grande do Sul.
DTW. Deutsche Tierarztliche Wochenschrift
|March 21, 1998
Summary
Calcinogenic plants like Solanum malacoxylon contain Vitamin D metabolites, primarily 1,25(OH)2D3 glycosides. These plant extracts show Vitamin D-like activity in chicks, with significant variations in potency among species.
Area of Science:
- * Plant Science
- * Biochemistry
- * Nutritional Science
Context:
- * Calcinogenic plants are known to contain Vitamin D and its metabolites.
- * Previous research suggests the active component is likely 1,25(OH)2D3 linked as a glycoside.
Purpose:
- * To evaluate the presence and activity of Vitamin D-like substances in four calcinogenic plants: Solanum malacoxylon, Cestrum diurnum, Trisetum flavescens, and Nierembergia veitchii.
- * To quantify the Vitamin D activity in these plant extracts using a chick model.
Summary:
- * Extracts from Solanum malacoxylon, Cestrum diurnum, Trisetum flavescens, and Nierembergia veitchii were administered to rachitic chicks.
- * Serum calcium, phosphorus, and alkaline phosphatase levels were analyzed to assess Vitamin D-like activity.
- * Solanum malacoxylon and Cestrum diurnum exhibited high activity, indicating the presence of 1,25(OH)2D3 glycosides, while Nierembergia veitchii and Trisetum flavescens showed lower concentrations.
- * Quantitative analysis revealed Vitamin D content ranging from 12,000 to 82,800 IU/kg across the studied plants, all concentrations being calcinogenic.
Impact:
- * This study confirms and quantifies Vitamin D-like activity in several calcinogenic plant species.
- * Identifies Solanum malacoxylon and Cestrum diurnum as significant sources of active 1,25(OH)2D3 glycosides.
- * Provides crucial data for understanding plant-based Vitamin D sources and their potential toxicity (calcinogenic effects).