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Related Experiment Videos

[Memory disorders in the elderly: complementary examinations--for whom?]

B Gueguen1, J Touchon, D Campion

  • 1Service de Neurophysiologie Clinique, Centre Hospitalier Sainte-Anne 1, Paris, France.

Therapie
|March 21, 1998
PubMed
Summary
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Diagnosing memory disorders in the elderly requires a multi-faceted approach. Brain imaging, neurophysiological tests, and genetic markers show promise for early and accurate detection of dementia.

Area of Science:

  • Neurology
  • Neuroscience
  • Geriatrics

Context:

  • Memory disorders in the elderly necessitate effective diagnostic strategies.
  • Current diagnostic methods include neurophysiological, neurobiological, and brain imaging studies.
  • Identifying reliable diagnostic markers remains a challenge.

Purpose:

  • To review the available diagnostic strategies for memory disorders in the elderly.
  • To evaluate the utility of various investigation types, including EEG, cognitive potentials, laboratory tests, genetic markers, and brain imaging.
  • To highlight the importance of brain imaging in diagnosing degenerative dementias.

Summary:

  • Electroencephalogram (EEG) and evoked potentials offer some diagnostic value, but lack consensus and standardization.

Related Experiment Videos

  • Laboratory tests like tau and P97 protein studies show promise, while genetic markers like apolipoprotein E phenotyping have diagnostic utility but are not predictive.
  • Morphological (CT, MRI) and functional (PET, SPECT) brain imaging are crucial for diagnosing dementias, with functional imaging particularly suited for degenerative types and early detection.

    • Impact:

    • This review aids clinicians in selecting appropriate diagnostic tools for elderly patients with memory impairments.
    • It underscores the critical role of advanced neuroimaging techniques in the early and accurate diagnosis of dementia.
    • Future research directions may focus on refining genetic and neurobiological markers for improved diagnostic and predictive capabilities.