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[Results of treatment of glaucoma associated with aniridia]
Insights
Secondary glaucoma in aniridia can often be managed with medication alone in children. Surgical interventions like cyclocryotherapy and trabeculectomy show limited success for this condition.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
Context:
- Secondary glaucoma in children with aniridia presents unique therapeutic challenges.
- Long-term management strategies for pediatric glaucoma are crucial.
Purpose:
- To retrospectively evaluate the therapeutic outcomes of secondary glaucoma associated with aniridia in pediatric patients.
- To assess the efficacy of medical and surgical interventions in managing this rare condition.
Summary:
- This study reviewed 11 children (22 eyes) with secondary glaucoma and aniridia since 1985.
- Initial treatment involved medications, with surgery (cyclocryotherapy, trabeculectomy) reserved for refractory cases.
- 19 out of 22 eyes achieved compensation, with 13 managed by medication alone. Surgical outcomes were relatively limited, with 6 operated eyes compensated.
Impact:
- Findings suggest that medical management can be effective for extended periods in pediatric secondary glaucoma with aniridia.
- Highlights the limited success of cyclocryotherapy and trabeculectomy, guiding future treatment considerations for this patient group.
Abstract:
The authors evaluate retrospectively the therapeutic results in secondary glaucoma with aniridia in 11 children (22 eyes) investigated since 1985. The mean age of the patients was 6.8 years. The examination under general anaesthesia was made in 10 children already during their first year and check-up examinations followed after 3-6 month intervals. Treatment of glaucoma was started by medicamentous therapy. If the effect was inadequate, cyclocryotherapy and trabeculectomy were used. Thirteen eyes are compensated by medicamentous treatment only, while surgical intervention was necessary in nine eyes of five children. A total of 20 operations were made, 12 times cyclocryotherapy and 8 times trabeculectomy, whereby the glaucoma is at present compensated in six operated eyes. A total of 19 eyes are compensated. The mean follow up period is 47 months in the operated patients and seven years in patients having medicamentous therapy. The analysis revealed that secondary glaucoma in aniridia can be compensated by mere medicamentous treatment for a number of years. If surgery is inevitable, cyclocryotherapy and trabeculectomy are only relatively successful.