[Principles of treatment for infected pseudarthoses]

Review of literature and own experience of the authors make them conclude, that assessment of extremity blood supply and precise bacteriologic evaluation with establishing the lowest efficient antibiotic concentration is necessary in planning of the treatment. It must include improvement of the blood supply by surgical reconstruction in case of impaired blood flow through great vessels and lumbar sympathectomy if crural arteries are compromised. Correct fixation of the fragments is equally important; the choice of the method depends on bony changes. Frequently, the management must be multi-stage. Improvement of the blood supply must always be included in the first stage. Rational surgical treatment supplemented by contemporary topical antibiotic administration allowed for termination of infection and bony union even in patients who were earlier considered for an amputation.