Animal models: new cholesterol raising and lowering nutrients
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Updated: Oct 30, 2026

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol
Published on: March 25, 2020
1Department of Food Science and Nutrition, University of Minnesota, St. Paul 55108-6099, USA. chassel@che2.che.umn.edu
Abstract:
Most reports reviewed here have used animal models to investigate the cholesterolemic effects of phytochemicals, herbal extracts, probiotic microorganisms, and plant constituents, including fibers. These compounds represent examples of what are termed 'functional foods' in that they elicit physiologic responses with implications for chronic disease prevention. These reports are examined in light of criteria developed from animal model experiments investigating fatty acid effects in order to aid the task of appropriate extrapolation of the results to humans.
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