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Hypertension and hemorheology
1National Institutes of Health, National Institute on Aging, Laboratory of Cellular and Molecular Biology, Baltimore, MD 21224, USA. ranjeet@helix.nih.gov
Clinical Hemorheology and Microcirculation
|March 21, 1998
Summary
Hypertension alters blood flow due to changes in red blood cells and flow forces. These hemorheological disturbances may worsen blood flow and contribute to bleeding disorders.
Area of Science:
- Cardiovascular Science
- Hematology
Background:
- Hypertension is linked to hemorheological disturbances.
- These disturbances involve red blood cell changes, fibrinogen interactions, and flow forces.
- Altered hemorheology, biochemistry, and vessel characteristics impact hemodynamics and may cause hemorrhagic disorders.
Purpose of the Study:
- To review hemorheological changes in hypertension.
- To explore the role of these changes in blood flow deterioration.
Main Methods:
- Literature review of hemorheological alterations in hypertension.
Main Results:
- Hypertension causes changes in red blood cell characteristics.
- Fibrinogen and flow forces influence red blood cell interactions.
- Hemorheological changes contribute to impaired blood flow dynamics.
Conclusions:
- Hemorheological disturbances are a significant factor in hypertension.
- These alterations play a probable role in the deterioration of blood flow.
- Understanding these changes is crucial for managing hypertension-related complications.