Structure-activity relationships for rat and mouse LD50 of miscellaneous alcohols
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Updated: Oct 13, 2026

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats
Published on: December 14, 2014
1Sino-Canadian High-tech Center of Resources and Environment, Chinese Academy of Siences, Beijing, China.
Abstract:
Structure-activity relationships between acute toxicities of 95 alcohols to rat and mouse (oral LD50) and four special sub-structure factors, hydroxyl number, carbon atom number were examined by means of expert system method. The results showed that the expert system based QSAR model was excellent for classification for miscellaneous alcohols (only 9 of them were wrong classified). It was also used to predict the toxicity of other 25 alcohols, and the false prediction rate was only 12%.
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