Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Monoarthropathy. Could this be infection?

D T Ma1, G J Carroll

  • 1Royal Perth Hospital.

Australian Family Physician
|March 21, 1998
PubMed
Summary

Diagnosing monoarthritis requires careful evaluation. Synovial fluid analysis is key to identifying joint inflammation causes, distinguishing between infection, crystals, or other conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Arthropathy in hereditary haemochromatosis segregates with elevated erythrocyte mean corpuscular volume.

Scandinavian journal of rheumatology·2020
Same author

K/B×N serum transfer arthritis is delayed and less severe in leukaemia inhibitory factor (LIF)-deficient mice.

Clinical and experimental immunology·2012
Same author

Characteristics of the arthropathy described in hereditary hemochromatosis.

Arthritis care & research·2011
Same author

Hereditary hemochromatosis is characterized by a clinically definable arthropathy that correlates with iron load.

Arthritis and rheumatism·2010
Same author

Ferritin concentrations in synovial fluid are higher in osteoarthritis patients with HFE gene mutations (C282Y or H63D).

Scandinavian journal of rheumatology·2010
Same author

Confirmation of two major polyarticular osteoarthritis (POA) phenotypes--differentiation on the basis of joint topography.

Osteoarthritis and cartilage·2009

Area of Science:

  • Rheumatology
  • Orthopedics
  • Internal Medicine

Background:

  • Monoarthritis in adults poses diagnostic challenges, potentially stemming from local joint issues, referred pain, periarticular syndromes, or polyarticular disease.
  • Differentiating true arthritis from other conditions like stress fractures is crucial.

Purpose of the Study:

  • To emphasize the critical importance of excluding sepsis in acute or subacute monoarthritis.
  • To highlight joint aspiration and synovial fluid analysis as essential diagnostic steps.

Main Methods:

  • Joint aspiration for synovial fluid collection.
  • Analysis of synovial fluid, including total and differential leucocyte counts.
  • Microscopy for crystals (polarized light) and organisms, plus culture.

Main Results:

  • Joint stiffness, restricted movement, and effusion suggest true arthritis.
  • Synovial fluid examination is the most informative diagnostic investigation.
  • Leucocyte counts, crystal presence, and microbial cultures aid in diagnosis.

Conclusions:

  • Synovial fluid analysis is paramount for diagnosing monoarthritis.
  • Identifying crystals, organisms, or specific leucocyte patterns helps differentiate causes.
  • Absence of crystals/organisms necessitates further analysis of fluid contents for diagnosis.

Related Experiment Videos