Coronary artery bypass surgery without cardiopulmonary bypass: short- and mid-term results
1Department of Cardiac Surgery and Anesthesiology Escorts Heart Institute and Research Centre, New Delhi.
Insights
Coronary artery bypass grafting without cardiopulmonary bypass is safe and effective, especially for high-risk patients. This approach demonstrated low mortality and high rates of angina-free survival post-procedure.
Area of Science:
- Cardiovascular Surgery
- Minimally Invasive Cardiac Surgery
Background:
- Coronary artery bypass grafting (CABG) is a standard treatment for coronary artery disease.
- Cardiopulmonary bypass (CPB) carries risks, particularly for patients with comorbidities.
- Off-pump coronary artery bypass grafting (OPCAB) offers an alternative to minimize CPB-related complications.
Purpose of the Study:
- To evaluate the safety and efficacy of OPCAB.
- To assess outcomes in high-risk patients undergoing OPCAB.
- To explore the role of transmyocardial laser revascularization (TMLR) in conjunction with OPCAB.
Main Methods:
- Retrospective analysis of 433 patients undergoing OPCAB between March 1994 and April 1997.
- Surgical approaches included midline sternotomy (277 patients) and minithoracotomy (156 patients).
- Combined OPCAB and TMLR was performed in 63 patients for complete revascularization.
Main Results:
- Hospital mortality was 2.3% (10/433), with four deaths due to ventricular arrhythmias.
- Average hospital stay was six days, with 91% of patients angina-free at follow-up.
- Myocardial perfusion scans showed significant improvement in reversible ischemia in patients who underwent combined OPCAB and TMLR.
Conclusions:
- OPCAB is associated with relatively low mortality, particularly in high-risk populations.
- TMLR is a viable option for achieving complete myocardial revascularization when combined with OPCAB.
- OPCAB provides excellent long-term angina-free survival rates.
Abstract:
From March 1994 to April 1997, 433 patients had undergone coronary artery bypass grafting without cardiopulmonary bypass in our institute. Sixty-eight patients had various organ dysfunctions and/or aortic atheroma or calcification and were regarded as high risk for cardiopulmonary bypass. In 277 patients surgery was performed through midline sternotomy, while in 156 minithoracotomy approach was used. In 361 patients single coronary artery bypass grafting was done, and in 72 two-coronary arteries were bypassed. In 63 patients who had graftable vessels in anterior wall and diffusely diseased ungraftable vessels in posterolateral and/or inferior wall, transmyocardial laser revascularisation was also done along with coronary artery bypass grafting to achieve complete myocardial revascularisation. Nine patients in this series were also subjected to simultaneous carotid endarterectomy along with myocardial revascularisation. In two patients complementary percutaneous transluminal coronary angioplasty of left circumflex coronary artery was done five days after minithoracotomy and left internal mammary artery to left anterior descending coronary artery bypass grafting. Forty-two cases were extubated in operating room. Average blood loss was 260 ml. Six patients were reexplored for postoperative bleeding. Seven patients had perioperative myocardial infarction. One developed neurological complication. Hospital mortality was 2.3 percent (10/433 cases) and four deaths were due to malignant ventricular arrhythmias. Nine patients developed chest wound complications. Average hospital stay after operation was six days, 423 patients were discharged from hospital and all of them were asymptomatic. During three years follow-up (range 3 to 38 months) there were three known cardiac deaths. Ninety percent (391) patients reported to the follow-up clinic and 91 percent of them were angina-free. In patients who were subjected to transmyocardial laser revascularisation along with coronary artery bypass grafting, myocardial perfusion scan showed a step-wise improvement in reversible ischemia. The perfusion index increased from 52 percent at three months to 90 percent at 12 months. We conclude that coronary artery bypass grafting without cardiopulmonary bypass can be done with relatively low mortality, more so in a group of patients in whom cardiopulmonary bypass poses a high risk. Transmyocardial laser revascularisation is a suitable means to provide complete myocardial revascularisation along with coronary artery bypass surgery in patients who have graftable vessels in anterior wall and ungraftable vessels in posterolateral and inferior walls.
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