[Analysis of rat enterocyte ultrastructure during glucose absorption]
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Updated: Aug 12, 2026

Methods to Study Epithelial Transport Protein Function and Expression in Native Intestine and Caco-2 Cells Grown in 3D
Published on: March 16, 2017
E S Snigirevskaia1, Ia Iu Komissarchik, M S Brudnaia
1Institute of Cytology, Russian Academy of Sciences, St. Petersburg.
Abstract:
Electronmicroscopic study of rat enterocytes under glucose load (10-40 mM) has shown some changes of their structure: aggregations of intramembrane particles of the apical membrane in the microvilli region, the dilitation of lateral intercellular spaces below tight junction, the condensation of actin near tight and intermediate junctions. The presence of these changes and almost absolute absence of destructions in tight junctions organization indicate that the main pathway of the isotonic fluid containing glucose across leaky epithelium of rat small intestine is a transcellular one.
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