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N-arylsubstituted-1-aryl-3,4-diphenyl-5-pyrazole amines with analgesic and antiarrhythmic properties
O Bruno1, S Schenone, A Ranise
1Istituto di Scienze Farmaceutiche dell'Università, Genova.
Farmaco (Societa Chimica Italiana : 1989)
|March 21, 1998
Abstract:
A series of N-aryl substituted-1-aryl-3,4-diphenyl-5-pyrazole amines was synthesized and evaluated for antiinflammatory, antihypertensive and platelet antiaggregating activities. Several of them were found to exhibit a significant analgesic and antiarrhythmic activity.