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Related Experiment Videos

Impending paradoxical embolism

R R Meacham1, A S Headley, M S Bronze

  • 1University of Tennessee-Memphis Lung Research Program and the Division of General Internal Medicine, USA.

Archives of Internal Medicine
|March 21, 1998
PubMed
Summary
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Paradoxical embolism, often linked to a patent foramen ovale, can cause arterial clots. Echocardiography aids in diagnosing this condition, which may lead to stroke.

Area of Science:

  • Cardiology
  • Neurology
  • Vascular Medicine

Background:

  • Paradoxical embolism is a critical diagnosis when arterial embolism originates from an unknown source alongside venous thromboembolism.
  • Echocardiography has increased the detection rate of impending paradoxical embolism.
  • A patent foramen ovale is present in up to 35% of the general population, serving as a potential pathway for paradoxical embolism.

Observation:

  • Patients with paradoxical embolism typically present with neurological deficits or signs of arterial embolism.
  • Pulmonary hypertension can create a right-to-left shunt via a patent foramen ovale.
  • This shunt allows venous thromboemboli to enter the arterial circulation, leading to paradoxical embolism.

Findings:

  • The study reviews a case of impending paradoxical embolism.

Related Experiment Videos

  • Literature pertinent to paradoxical embolism is discussed.
  • The frequency of paradoxical embolism as a cause of stroke is significant, potentially accounting for 47,000 strokes annually in the US.

    • Implications:

    • Paradoxical embolism must be considered in cases of unexplained arterial embolism, especially with concurrent venous thromboembolism.
    • Early diagnosis and management are crucial to prevent severe outcomes like stroke.
    • Understanding the role of patent foramen ovale and pulmonary hypertension is key to identifying at-risk individuals.