[Use of bicycle ergometry test for studying metabolism in women during long-term hypokinesia]

Studies performed under conditions of a 120-day HDT in the female human subjects demonstrated that out of 20 biochemical parameters of the blood characterizing the carbohydrate and lipid exchange only 14 indices changed significantly during hypokinesia. As this takes place, the maximum number of changes was revealed with the help of the graded physical load test (GPL-test) and only in case of 9 indices the alterations were found at rest. Physical loads which have been used during HDT as the preventive measures had no effect only on insignificant part of metabolic shifts such as hypokinesia-associated increase of an activity of blood lactate dehydrogenase and relative content of phosphatidylcholine as well as an increased blood content of phosphates and decreased relative portion of phospholipids which also revealed with the aid of GPL-test. All other changes which have been revealed in HDT both at rest (increased blood level of triglycerides, lactate, relative content of free fatty acids, free cholesterine and sphingomyelin with augmented decrease in glucose concentration) as well as with the help of GPT-test (an increase of absolute blood content of free fatty acids with a decrease in their relative content; an increase of the relative content of total cholesterine with decreased portion of cholesterine ethers) have been stopped.