Related Experiment Video
Updated: Aug 11, 2026
09:26
Preparation and Using Phantom Lesions to Practice Fine Needle Aspiration Biopsies
Published on: September 29, 2009
Nonhealing extraction sites: two case reports and a differential diagnosis
1Department of Oral and Maxillofacial Surgery, Tufts University School of Dental Medicine, USA.
Journal of the Massachusetts Dental Society
|April 1, 1994
Summary
Squamous cell carcinoma (SCC) can occur with third molars, often diagnosed post-extraction. Early detection and follow-up are crucial for managing these rare but serious oral cancer cases.
Area of Science:
- Oral pathology
- Dental oncology
- Surgical pathology
Background:
- Squamous cell carcinoma (SCC) is the most common oral malignancy.
- Third molars (wisdom teeth) are frequently impacted and surgically removed.
- Rarely, oral SCC can be associated with third molar extraction sites.
Observation:
- Two cases are presented where SCC diagnosis was confirmed after third molar removal.
- Patients presented with slow-healing, painful extraction sites, mimicking common post-operative complications.
- Clinical presentation included persistent pain, swelling, and delayed healing post-third molar extraction.
Findings:
- Histopathological examination of the extraction sockets confirmed squamous cell carcinoma in both cases.
- The diagnosis was established post-operatively, highlighting a diagnostic challenge.
- Differential diagnosis for persistent post-extraction symptoms is critical.
Implications:
- Emphasizes the importance of vigilant postoperative follow-up for third molar extraction sites.
- Highlights the need for prompt diagnostic intervention when symptoms persist or are atypical.
- Timely management of oral SCC associated with third molars can reduce patient morbidity and improve outcomes.
