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[Nutritional fetal rickets. A case report]

M H Blond1, F Gold, F Pierre

  • 1Service de Médecine Néonatale, Centre de Pédiatrie Gatien de Clocheville, Tours.

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|January 1, 1997
PubMed
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Maternal vitamin D deficiency can cause fetal rickets and neonatal hypocalcemia. Supplementation during pregnancy is crucial for fetal calcium supply and preventing infant deficiencies.

Area of Science:

  • Neonatal Health
  • Maternal-Fetal Medicine
  • Nutritional Biochemistry

Background:

  • Vitamin D is essential for calcium absorption and bone health.
  • Maternal vitamin D deficiency can impact fetal development and neonatal calcium homeostasis.
  • Cultural practices and limited sun exposure can contribute to vitamin D deficiency in pregnant women.

Observation:

  • A newborn presented with congenital rickets (craniotabes) and severe hypocalcemia.
  • Radiographic evidence confirmed fetal rickets.
  • The mother exhibited signs of prolonged nutritional and vitamin D deficiency, linked to limited sun exposure and low dietary intake.

Findings:

  • Severe maternal vitamin D deficiency was identified as the cause of fetal rickets and neonatal hypocalcemia.

Related Experiment Videos

  • The case highlights the critical role of maternal vitamin D in fetal skeletal development and calcium transfer.
  • Radiography confirmed the diagnosis of rickets in the newborn.

    • Implications:

    • Emphasizes the necessity of vitamin D screening and supplementation during pregnancy to prevent fetal rickets and neonatal hypocalcemia.
    • Recommends specific vitamin D supplementation protocols for pregnant women, including daily intake or high-dose regimens.
    • Underscores the importance of addressing nutritional deficiencies in pregnant populations, particularly those with limited sun exposure.