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Related Experiment Videos

Lacunar infarctions presenting as memory loss and mental changes: four cases report

Y H Tseng1, S J Ryu

  • 1Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.

Changgeng Yi Xue Za Zhi
|March 24, 1998
PubMed
Summary

Lacunar infarction, typically affecting motor function, can surprisingly cause acute amnesia and mental changes. These higher cortical dysfunctions, though uncommon, highlight the brain

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Area of Science:

  • Neurology
  • Neuroscience
  • Cerebrovascular Diseases

Background:

  • Lacunar infarctions are small, deep brain infarcts often associated with motor deficits.
  • Impairment of higher cortical functions is not typically considered a primary manifestation of lacunar strokes.

Observation:

  • This study reports on four patients presenting with acute amnesia and altered mental status.
  • The patients experienced lacunar infarctions in strategically critical brain regions, including the thalamus and the genu of the internal capsule.

Findings:

  • Lacunar infarcts in specific locations, such as the thalamus and internal capsule genu, can lead to significant cognitive and memory impairments.
  • The observed cognitive deficits ranged from transient to persistent, affecting three out of the four patients.

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Implications:

  • These findings challenge the traditional view of lacunar infarction presentation.
  • Recognizing cognitive impairment as a potential symptom of lacunar stroke is crucial for accurate diagnosis and management.
  • This underscores the importance of detailed neurological examination and neuroimaging in cases of unexplained cognitive decline.