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Proposed cutoff values to define bladder outlet obstruction in women
S Chassagne1, P A Bernier, F Haab
1Department of Urology and Academic Computing Services (Biostatistics), The University of Texas Southwestern Medical Center, Dallas 75235-9110, USA.
Urology
|March 24, 1998
Summary
This study establishes preliminary cut-off values for diagnosing female bladder outlet obstruction using pressure-flow studies. These findings aim to refine the current diagnostic criteria for this condition.
Area of Science:
- Urology
- Female Lower Urinary Tract Dysfunction
- Urodynamics
Background:
- The diagnosis of bladder outlet obstruction in women lacks a standardized urodynamic definition.
- Current diagnostic methods rely on subjective patient history and imaging, leading to potential inaccuracies.
Purpose of the Study:
- To develop a pressure-flow nomogram (PdetQmax/Qmax) for women.
- To establish specific cut-off values for peak detrusor pressure and flow rate to define obstruction.
Main Methods:
- Prospective study of 124 control and 35 obstructed women undergoing complete urodynamic evaluation.
- Pressure-flow plots and receiver operator characteristic (ROC) curves were used to determine optimal cut-off values.
Main Results:
- ROC curve analysis identified potential cut-off values for peak flow rate (Qmax) and detrusor pressure at maximal flow (PdetQmax).
- Combined cut-off values (Qmax ≤ 15 mL/s and PdetQmax > 20 cm H2O) demonstrated high specificity (91.1%) for obstruction.
Conclusions:
- Preliminary cut-off values for pressure-flow parameters were established.
- These values offer a foundation for a more objective, urodynamic definition of outlet obstruction in women.
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