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Updated: Jul 29, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Localized squamous cell carcinoma of the bladder causing hypercalcemia and inhibition of PTH secretion
J D Wolchok1, H W Herr, W K Kelly
1Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Abstract:
We report a case of symptomatic hypercalcemia in a patient with muscle-invasive, resectable squamous cell carcinoma of the bladder. Serum parathyroid hormone was consistent with secretion of parathyroid hormone-related protein. After radical cystoprostatectomy, calcium levels returned to normal. Patients with squamous cell carcinoma and an abnormal serum calcium level may have localized disease and should not be denied definitive local therapy.
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