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Related Experiment Videos

Bronchial asthma induced by rice

T Arai1, T Takaya, Y Ito

  • 1Division of Internal Medicine, Gifu University School of Medicine.

Internal Medicine (Tokyo, Japan)
|March 24, 1998
PubMed
Summary

This case study highlights a rare instance of adult-onset, severe grain-induced asthma. The patient developed a positive allergy test to rice after previously being sensitized to mites and dust.

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Area of Science:

  • Allergy and Immunology
  • Respiratory Medicine
  • Clinical Case Study

Background:

  • Bronchial asthma can be triggered by various environmental allergens.
  • Food allergies, particularly grain-induced asthma, present complex diagnostic challenges.
  • Sensitization patterns can evolve over time in allergic individuals.

Observation:

  • A 43-year-old male initially presented with asthma triggered by mites and house dust.
  • Two years later, the patient experienced a severe asthma attack with a positive Immunoglobulin E (IgE) radioallergosorbent test (RAST) for rice.
  • Concurrently, IgE RAST results for mites and house dust became negative.

Findings:

  • This case demonstrates a rare progression to severe, adult-onset, grain-induced bronchial asthma.

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  • The shift in allergen sensitivity from environmental factors to a specific food (rice) is unusual.
  • Hypoallergenic rice successfully managed the patient's asthma symptoms.

    • Implications:

    • This case underscores the need for comprehensive allergy testing, including food allergens, in refractory asthma.
    • It suggests that allergen sensitization can change, potentially leading to new-onset food-induced respiratory conditions.
    • Further research into the mechanisms of food-induced asthma and evolving sensitization is warranted.