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[Weak-flow membrane blood oxygenation in treatment of patients with peritonitis]
Abstract:
The application of the level of molecules with medium molecular mass (MM) and wave length E254 and 280 nm was tried in 30 patients, operated on for various diseases of the organs of abdominal cavity and their purulent complications. Besides routine treatment weak flow membrane blood oxygenation was carried out. As a result of the study it was established that the level of medium molecular peptides appears to be a criteria of effectiveness of the weak-flow membrane blood oxygenation and determines duration of the procedure. The initial concentration of MM from 1,0 relative units and more duration of the blood oxygenation period should be limited by 2 hours. This method can be regarded, as independent mode od detoxication.
Insights
Monitoring medium molecular peptides (MM) can guide weak-flow membrane blood oxygenation in abdominal surgery patients. High MM levels indicate limiting treatment to two hours for effective detoxification.
Area of Science:
- Biochemistry
- Medical Technology
- Surgical Complications
Context:
- Patients undergoing abdominal surgery often develop purulent complications.
- Assessing the effectiveness of detoxification methods is crucial in managing these patients.
- Weak-flow membrane blood oxygenation is an adjunctive treatment modality.
Purpose:
- To evaluate the utility of medium molecular mass (MM) levels as a biomarker for weak-flow membrane blood oxygenation effectiveness.
- To determine optimal treatment duration for weak-flow membrane blood oxygenation based on MM levels.
- To assess the potential of weak-flow membrane blood oxygenation as a standalone detoxification method.
Summary:
- The study monitored medium molecular mass (MM) levels using spectrophotometry (E254 and 280 nm) in 30 patients with abdominal surgical complications.
- Weak-flow membrane blood oxygenation was employed alongside routine treatment.
- Results indicate that MM levels serve as a key indicator for the efficacy of this procedure, guiding treatment duration.
Impact:
- Establishing MM concentration thresholds can optimize weak-flow membrane blood oxygenation protocols.
- A threshold of 1.0 relative units for initial MM concentration suggests limiting treatment to 2 hours.
- This research supports weak-flow membrane blood oxygenation as a potential independent detoxification strategy in surgical patients.