Frequency shift analysis of tetracycline
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S A Nabi1, E S Abu-Nameh, M I Helaleh
1Department of Chemistry, Aligarh Muslim University, India.
Acta Poloniae Pharmaceutica
|May 1, 1997
Abstract:
A spectrophotometric determination of tetracycline is described based on the wavelength shift in the absorption maxima (lambda max 360 nm) of tetracycline solutions in water caused by the hydrogen bonding between protons of tetracycline and the oxygens of DMSO. Tetracycline was determined in the range of 0.04 to 0.18 ppm. The method was also successfully applied to spiked urine samples.

