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Menetrier's disease presenting with iron deficiency anemia
M L Wilkerson1, S C Meschter, R E Brown
1Division of Laboratory Medicine, PennState Geisinger Health System, Danville 17822-0131, USA.
Annals of Clinical and Laboratory Science
|March 26, 1998
Summary
Menetrier
Area of Science:
- Gastroenterology
- Pathology
Background:
- Menetrier's disease (MD) is a rare hypertrophic gastropathy.
- MD can mimic gastric carcinoma or lymphoma, complicating diagnosis.
Observation:
- A 41-year-old female presented with fatigue, dyspnea, pallor, and edema.
- Endoscopy revealed a gastric mass; CT suggested lymphoma or carcinoma.
- Histopathology confirmed MD with ulcerated hypertrophied folds.
Findings:
- The patient's symptoms were attributed to severe iron deficiency anemia caused by ulcerated hypertrophied gastric folds in MD.
- Immunohistochemistry for transforming growth factor-alpha supported the MD diagnosis.
Implications:
- Recognizing MD's potential to present with anemia is crucial for differential diagnosis.
- This case highlights the importance of considering MD in patients with unexplained anemia and gastric abnormalities.
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