[Blood immunoglobulin deficiencies during bronchial asthma in the adult]

The study of serous immunoglobulins of 500 asthmatic patients enabled the authors to discover a deficit in one of the Ig in 93 cases (18.6%), mainly in cases of intrinsic allergic asthma with an important or dominant infectious character, or microbial asthma. It concerned partial shortages of usually only one Ig in each patient, mostly the IgG. The importance of these deficits is discussed, particularly in the origin of bacterial sensitivity of these asthmas and in the genesis of atopy. The problem of IgG reagins is also discussed. Practical deductions drawn form these findings are envisaged.