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Related Experiment Videos

[Scleroderma with anomalies of the thyroid function. 7 cases]

E Ghayad1, A Tohme, F Haddad

  • 1Service de Médecine Interne, Beyrouth, Liban, Université Saint-Joseph, Faculté de Médecine.

Annales De Medecine Interne
|January 1, 1997
PubMed
Summary
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Scleroderma patients often have thyroid issues, with 7 of 36 showing abnormalities like hypothyroidism or hyperthyroidism. Regular thyroid screening is recommended for systemic sclerosis patients due to this common association.

Area of Science:

  • Endocrinology
  • Rheumatology
  • Immunology

Context:

  • Scleroderma, a systemic autoimmune disease, can affect various organs.
  • Thyroid dysfunction is a known comorbidity in autoimmune conditions.

Purpose:

  • To investigate the prevalence of thyroid abnormalities in patients with systemic sclerosis.
  • To determine the types of thyroid dysfunction associated with scleroderma.

Summary:

  • Thyroid function was assessed in 36 scleroderma patients.
  • Seven patients (19.4%) exhibited thyroid dysfunction: 6 with hypothyroidism (autoimmune thyroiditis) and 1 with hyperthyroidism (Graves' disease).
  • Hypothyroid patients had localized or diffuse systemic sclerosis; 2 also had Sjögren syndrome. The hyperthyroid patient had diffuse systemic sclerosis.

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Impact:

  • Highlights a significant association between scleroderma and thyroid diseases.
  • Recommends routine thyroid screening for all systemic sclerosis patients.
  • Suggests potential shared autoimmune pathways contributing to both conditions.