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Updated: Aug 10, 2026

An Efficient and High Yield Method for Isolation of Mouse Dendritic Cell Subsets
Published on: April 18, 2016
Dendritic cells
1Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Headington, UK.
Abstract:
Dendritic cells are potent stimulators of immune responses against foreign antigens. Recent advances in this area include the delineation of distinct developmental pathways for different dendritic cell subsets; the emerging concept that one dendritic cell subset has regulatory functions that may contribute to induction of tolerance to self antigens; increased understanding of the interaction of dendritic cells with microbial products and viruses, such as HIV; and the application of dendritic cells for immunotherapy in certain cancers and possibly for the induction of transplantation tolerance.
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