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Medication-induced gingival enlargement: a clinical review
L H Silverstein1, J J Garnick, M Szikman
1Department of Periodontics, Medical College of Georgia, Augusta, USA.
General Dentistry
|July 1, 1997
Abstract:
This review discusses the etiology and treatment of gingival hyperplasia. It cites evidence that medications such as phenytoin, an anticonvulsant; cyclosporine, an immunosuppressant; and numerous calcium channel blocking agents have been shown clinically and histologically to produce analogous gingival enlargements. A multiphasic approach to treating disfiguring gingival hyperplasia through mechanical and chemical plaque control, in conjunction with the surgical removal of the hyperplastic tissue, is discussed.