Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Is splenectomy more dangerous for massive spleens?

D McAneny1, W W LaMorte, T E Scott

  • 1Section of Surgical Oncology, Boston University, Massachusetts, USA.

American Journal of Surgery
|March 27, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Understanding occipital pressure sores in UK military casualties: a pilot study in healthy military personnel.

BMJ military health·2023
Same author

A comparison of CT lung voxel density analysis in a blast and non blast injured casualty.

Journal of the Royal Army Medical Corps·2018
Same author

Establishing and maintaining a robust Role 2 Afloat organisation within the Royal Naval Medical Services.

Journal of the Royal Naval Medical Service·2018
Same author

Prone position ventilation in the Role 2 Afloat environment.

Journal of the Royal Naval Medical Service·2018
Same author

Primary blast lung injury simulator: a new computerised model.

Journal of the Royal Army Medical Corps·2018
Same author

Primary blast lung injury - a review.

British journal of anaesthesia·2017

Splenectomy risks are not higher for massive spleens. Age and underlying illness, not spleen size, are key factors for complications and death after spleen removal for hematologic diseases.

Area of Science:

  • Surgical Oncology
  • Hematology
  • Clinical Risk Assessment

Background:

  • Debate exists regarding increased risks associated with removing massive spleens (> or = 1500 g) compared to smaller ones (< 1500 g).
  • Understanding the specific hazards of splenectomy is crucial for patient management.

Purpose of the Study:

  • To determine the actual risks and hazards of splenectomy, particularly in relation to spleen size.
  • To investigate the influence of spleen size on postoperative complications and mortality.

Main Methods:

  • A review of 223 consecutive adult patients undergoing elective splenectomies for hematologic diseases.
  • Morbidity and mortality rates were analyzed and combined with published data for a comprehensive meta-analysis.

Main Results:

Related Experiment Videos

  • Patients with massive spleens showed higher initial rates of postoperative complications (RR 2.1) and death (RR 4.7).
  • However, after adjusting for comparable diagnoses, spleen size did not significantly impact complication (RR 1.4) or mortality (RR 2.1) rates.
  • Multivariate analysis identified advanced age as a critical risk factor for both complications and death.

Conclusions:

  • Increased age and the presence of underlying illnesses are the primary determinants of morbidity and mortality following splenectomy for hematologic conditions.
  • Spleen size is not an independent risk factor for adverse outcomes when age and diagnosis are considered.