Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Papillary thyroid carcinoma: modified radical neck dissection improves prognosis

S Noguchi1, N Murakami, H Yamashita

  • 1Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan.

Archives of Surgery (Chicago, Ill. : 1960)
|March 28, 1998
PubMed
Summary

Modified radical neck dissection benefits specific papillary thyroid cancer patients. Those with nodal metastasis, extrathyroidal invasion, or women over 60 show improved survival with this procedure.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of Supine-Use Wearable Cyborg for Treatment of Neurogenic Bowel Dysfunction after Spinal Cord Injury.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Development of Wearable Cyborg HAL Ankle Joint Unit to improve ankle joint function during gait.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Micrometer-scale monolayer SnS growth by physical vapor deposition.

Nanoscale·2020
Same author

A case of combined laparoscopic reduction and open preperitoneal mesh repair for incarcerated small bowel in a retroperitoneal hernia between the external and internal iliac vessels.

Hernia : the journal of hernias and abdominal wall surgery·2016
Same author

Development of an MR-compatible configurable brush stimulation device.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2015
Same author

High-dose chemotherapy for high-risk retinoblastoma: clinical course and outcome of 14 cases in the National Cancer Center, Japan.

Bone marrow transplantation·2014

Area of Science:

  • Oncology
  • Surgical Oncology
  • Endocrine Surgery

Background:

  • Papillary thyroid cancer (PTC) is the most common thyroid malignancy.
  • Neck dissection is a critical component in the surgical management of PTC.
  • The extent of neck dissection, particularly modified radical neck dissection (MRND), requires careful consideration for optimal patient outcomes.

Purpose of the Study:

  • To evaluate the survival benefit of modified radical neck dissection (MRND) in specific patient subsets with papillary thyroid cancer.
  • To identify risk factors influencing outcomes in patients undergoing surgical treatment for papillary thyroid cancer.

Main Methods:

  • Retrospective cohort study of 2966 patients treated between 1946 and 1991.
  • Analysis included patients with primary tumors ≥1 cm undergoing curative treatment.

Related Experiment Videos

  • Surgical approaches included MRND (72.1%), partial node excision (8.5%), and no node excision (19.4%).

    • Main Results:

    • Univariate and multivariate analyses identified significant risk factors: sex, age, primary tumor size, extrathyroidal invasion, and nodal metastasis.
    • A subset of patients demonstrated a survival advantage with MRND.
    • Key predictors of outcome included age, tumor characteristics, and presence of metastasis.

    Conclusions:

    • Modified radical neck dissection (MRND) offers survival benefits for select papillary thyroid cancer patients.
    • Patients with nodal metastasis, extrathyroidal tumor invasion, and women over 60 years old are identified as beneficiaries of MRND.
    • These findings support tailored surgical approaches in managing papillary thyroid cancer based on individual risk factors.