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Exercise tolerance at 4 and 6 ATA

N R Anthonisen, G Utz, M H Kryger

    Undersea Biomedical Research
    |June 1, 1976
    PubMed
    Summary
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    This study found that breathing 0.2 ATA oxygen in nitrogen at increased atmospheric pressures (4-6 ATA) did not affect maximum oxygen uptake or heart rate during exercise. However, high-intensity exercise at 6 ATA caused decreased ventilation and potential nitrogen narcosis.

    Area of Science:

    • Physiology
    • Hyperbaric Medicine
    • Exercise Science

    Background:

    • Understanding physiological responses to hyperbaric environments is crucial for diving and occupational safety.
    • Previous research has explored the effects of increased atmospheric pressure on human performance, but specific data on exercise at varying oxygen partial pressures remain limited.

    Purpose of the Study:

    • To investigate the physiological effects of breathing 0.2 ATA O2 in nitrogen at 4 and 6 ATA during graded bicycle exercise.
    • To assess exercise capacity, cardiorespiratory responses, and potential adverse effects like dyspnea and narcosis under hyperbaric conditions.

    Main Methods:

    • Seven healthy males performed 5-minute bicycle ergometer tests at 50-100% maximum oxygen uptake at 4 ATA and three subjects were also studied at 6 ATA.
    • Subjects breathed a gas mixture of 0.2 ATA O2 and the remainder nitrogen.

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  • Measurements included oxygen uptake, carbon dioxide output, heart rate, ventilation, and respiratory frequency.

    • Main Results:

    • All subjects achieved maximum work capacity at all tested pressures.
    • No significant pressure-dependent changes were observed in heart rate, oxygen uptake, or carbon dioxide output.
    • Ventilation decreased at exercise levels exceeding 80% maximum oxygen uptake at 4 and 6 ATA, indicating minor CO2 retention.
    • Severe dyspnea was reported when ventilation approached maximum breathing capacity.
    • At 6 ATA, heavy exercise led to disturbances in consciousness, attributed to nitrogen narcosis.

    Conclusions:

    • Breathing 0.2 ATA O2 in nitrogen at 4-6 ATA does not limit maximal exercise capacity or alter key metabolic and cardiovascular responses.
    • Ventilatory adjustments occur at high exercise intensities, with potential for dyspnea and nitrogen narcosis at 6 ATA.
    • These findings have implications for understanding physiological limits during hyperbaric exposures involving exertion.