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Divergent corticostriatal projections from a single cortical column in the somatosensory cortex of rats
K D Alloway1, J J Mutic, J E Hoover
1Department of Neuroscience and Anatomy, Pennsylvania State University, Hershey, PA 17033, USA. kalloway@psuhmc.hmc.psu.edu
Abstract:
We injected biotinylated dextran amine (BDA) into single vibrissal 'barrels' of primary somatosensory (SI) cortex and reconstructed the topography of labelled varicosities in the dorsolateral caudate-putamen. Plots of labelled varicosities revealed densely-packed clusters of corticostriatal arborizations along the dorsolateral edge of the caudate-putamen and sparsely-packed arborizations more medially. The medial and lateral clusters of labelled terminals were separated by regions of unlabelled neuropil and lead us to conclude that a single cortical column sends divergent projections to multiple regions of the caudate-putamen.